Productivity enhancement of C=C bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes.

نویسندگان

  • Elisabetta Brenna
  • Francesco G Gatti
  • Daniela Monti
  • Fabio Parmeggiani
  • Alessandro Sacchetti
چکیده

To overcome the usually low productivities of the C=C bond bioreduction of α,β-unsaturated aldehydes we combined the in situ substrate feeding product removal (SFPR) technology with a cascade system comprising an isolated ene-reductase and a chemoselective alcohol dehydrogenase.

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عنوان ژورنال:
  • Chemical communications

دوره 48 1  شماره 

صفحات  -

تاریخ انتشار 2012